RP2040 on batteries: ~180 µA even in deep sleep, and an internal temperature sensor you must calibratewarning · unverified · RP2040 typically draws around 180 µA even in deep sleep, so Raspberry Pi recommends powering it off completely for minimal standby current (3V3_EN turns a Pico off). Its internal temperature sensor is low-resolution and inaccurate unless calibrated against a known ADC reference voltage.
Raspberry Pi Pico family: RP2040 vs RP2350, and which Pico has wirelesscomparison · unverified · Pico and Pico W use RP2040 (dual Cortex-M0+, 133 MHz, 264 kB SRAM); Pico 2 and Pico 2 W use RP2350 (dual Cortex-M33 or Hazard3 RISC-V, 150 MHz, 520 kB SRAM, security features). Only the W models have Wi-Fi and Bluetooth.